![]() ![]() Such symptoms can hinder the smooth contraction of digestive tract muscles (peristalsis) and lead to constipation or even diarrhea. The pressure in the stomach resulting from gas can also cause nausea, heartburn, and spastic abdominal pain primarily located near the navel and right lower abdomen. On account of the build-up of gas, someone with SIBO usually feels bloated, experiences excessive flatulence, burps, and has bad breath. Symptoms of SIBO can present 30-90 minutes after eating and they are triggered by bacteria caused malabsorption. Additional mechanisms which prevent the spread of bacteria in the small intestine include immunoglobulins in the mucous membrane, pancreatic juice, and gall bladder bile. Both the ileocecal valve, which separates the small intestine from the large intestine, and peristaltic waves, which ensure that digestive tract muscles contract smoothly, prevent the infiltration of large intestine bacterial flora into the small intestine. These bacteria have numerous physiological functions, one of which is the further digestion of fermented food from the small intestine. The large intestine, on the contrary, houses a thick layer of bacteria consisting of approximately 10 10-10 12 bacteria per milliliter. ![]() ![]() Bacteria ingested through eating are predominantly killed by gastric acid, which means that only minimal amounts of bacteria are detectable in the small intestine. In its normal physiological state, the small intestine contains a small amount of bacteria, approximately 10 3-10 4 bacteria per milliliter. Small intestinal bacterial overgrowth (SIBO) is a disorder whereby bacteria excessively grows in the small intestine it is not a severe disorder and does not lead to organ damage. ![]()
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